|Topic:||Triose Phosphate Isomerase .|
|Details:|| The two products of the aldolase A reaction equilibrate readily in a reaction catalyzed by triose phosphate isomerase (TPI). Succeeding reactions of glycolysis utilize G3P as a substrate; thus, the aldolase A reaction is pulled in the glycolytic direction by mass action principals. The triose phosphate isomerase gene (gene symbol: TPI1) is located on chromosome 12p13.31 and is comprised of 8 exons that generate three alternatively spliced mRNAs, each of which encode a distinct protein isoform.
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