|Topic:||The uronic acid pathway. .|
|Details:||The pathway involves the oxidation of glucose-6-phosphate to UDP-glucuronate. The oxidation is uncoupled from energy production. UDP-glucuronate is used in the synthesis of glycosaminoglycan and proteoglycans as well as forming complexes with bilirubin, steroids and certain drugs. The glucuronate complexes form to solubilize compounds for excretion. The synthesis of ascorbate (vitamin C, L-ascorbate) from UDP-glucuronate does not occur in primates.|
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