|Topic:||Catabolism of the catecholamine neurotransmitters. .|
|Details:||Only clinically important enzymes are included in this diagram. The catabolic byproducts of the catecholamines, whose levels in the cerebrospinal fluid are indicative of defects in catabolism, are in blue underlined text. Abbreviations: TH: tyrosine hydroxylase, QDPR: quinoid dihydropterine reductase (more commonly called dihydropteridine reductase), H2B: dihydrobiopterin, H4B: tetrahydrobiopterin, MAO: monoamine oxidase, COMT: catecholamine-O-methyltransferase, MHPG: 3-methoxy-4-hydroxyphenylglycol, DOPAC: dihydroxyphenylacetic acid.|
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